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ASCP ASCP-MLT Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Blood Banking | 15–20% | - Transfusion practice and testing - Blood products and components - Blood group systems and immunology |
| Chemistry | 20–25% | - Carbohydrates, lipids, and enzymes - Electrolytes, acid-base, and toxicology |
| Immunology | 5–10% | - Principles of immunology - Serologic procedures and immune diseases |
| Hematology | 20–25% | - Physiology and disease states - Laboratory testing and hemostasis |
| Laboratory Operations | 5–10% | - Quality assessment and safety - Instrumentation and laboratory mathematics |
| Microbiology | 15–20% | - Virology and parasitology testing - Bacteriology and mycology procedures |
| Urinalysis and Other Body Fluids | 5–10% | - Physical and chemical testing - Microscopic analysis and disease correlation |
ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:
1. Intravascular hemolysis is typically associated with increased levels of serum (plasma) LDH and bilirubin, and an increased number of reticulocytes. Serum LDH is found in higher levels during intravascular hemolysis due to fact that high levels of LDH are normally found within the red cells, but is now being spilled into the bloodstream via red cell lysis. Bilirubin is a breakdown product of hemoglobin, which has also been spilled into the bloodstream from broken red blood cells via hemolysis. Reticulocytosis is a reflection of the release of an increased number of immature red blood cells from the marrow to account for the red blood cells that are lost through hemolysis. This is a normal response. Failure to show an increased reticulocyte count with hemolytic episodes or hemorrhage would indicate an ineffective erythropoiesis (possible bone marrow function problem).
Which of these blood levels will increase during intravascular hemolysis?
A) All of the above
B) Serum (plasma) LDH
C) Serum (plasma) bilirubin
D) None of the above
E) Reticulocytes
2. Kell, Kidd, and Duffy are usually warm reacting IgG antibodies. The most common P system antibody is anti-P1, which is a frequently naturally occurring low titer IgM antibody, seen in most P2 individuals.
Blood bank
Which of the following blood groups is most frequently associated with cold agglutinins:
A) Duffy
B) Kidd
C) Kell
D) P
3. Alkaline phosphatase, or ALP, is present in kidneys, liver, intestines, bone, and the placenta. The liver makes the largest amount of ALP. Some of the conditions associated with increased levels of ALP include: damaged liver cells, rapid bone growth (during puberty), bone diseases, or a disease that affects how much calcium is in the blood (hyperparathyroidism), and vitamin D deficiency.
Chemistry
Isoenzymes of alkaline phosphatase occur in:
A) Kidney, bone, intestines, liver
B) Brain, kidney, intestines, bone
C) Bone, brain, liver, pancreas
D) Liver, brain, spleen, intestines
4. Free T4 is affected the least by changes in plasma proteins during pregnancy.
Which of the following thyroid function assays is affected least by pregnancy:
A) Total T4
B) Free T4
C) Total T3
5. In healthy individuals, procalcitonin is only synthesized by the thyroid C cells. In bacterial infections, PCT is synthesized in various extrathyroidal neuroendocrine tissues.
In healthy individuals, procalcitonin is synthesized by which cells in the body?
A) Leukocytes
B) Red blood cells
C) Thyroid C cells
D) Hepatocytes
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: D | Question # 3 Answer: A | Question # 4 Answer: B | Question # 5 Answer: C |
